Haohong Pharmaceutical

Apalutamide intermediates,Abemaciclib intermediates,Alectinib intermediates

Founded
2021
Headquarters
Name:Xu Tianxia Email: Xutx@haohong-pharma.com Tel: +86 180-6854-1569 WhatsApp: +86 180-6854-1569 Address: Block B, building 3, accelerator, high tech Zone, Qihe County, De Zhou City, Shandong Province, China
Factory Area
3000㎡
Employees
75
Export Ratio
40%

About Us

Haohong (Qihe) Pharmaceutical Technology Co., Ltd. is located in the High-tech Zone of Qihe County, Shandong Province, adjacent to the Yellow River and within the Jinan Economic Circle, enjoying convenient transportation. The company specializes in the R&D and custom production of innovative active pharmaceutical ingredients (APIs) and pharmaceutical intermediates. It passed the ISO 9001:2015 quality management system certification in 2021, was recognized as a Technology-based Small and Medium-sized Enterprise in 2024, and awarded Innovative Small and Medium-sized Enterprise of Shandong Province in 2025. Haohong has a high-level R&D team and a full range of analytical testing instruments and methods. At present, its production base in Liaocheng is equipped with 30 sets of 3,000–5,000L reactors, with an annual production capacity of 1,000 tons. The company focuses on the development of active pharmaceutical ingredients and intermediates for anti-cancer, anti-hepatitis C and anti-diabetic therapies, with an emphasis on high-grade intermediates. Its main products include Bicalutamide, Enzalutamide, Apalutamide, Darolutamide, Abemaciclib, Venetoclax, Macitentan, Empagliflozin, Larotrectinib, Apixaban, Rivaroxaban, Ibrutinib, Ceritinib, Pomalidomide, Lenalidomide, Ivacaftor, Tofacitinib, Cabozantinib, Alectinib, etc. Our products are exported to overseas markets including the United States, Europe, Japan, India, Bangladesh and other regions. The company currently has dozens of high-grade intermediates available for commercial production, and also provides customers with efficient custom synthesis services ranging from gram scale to hundreds of kilograms. Adhering to the corporate philosophy of "Pragmatism, Innovation, Integrity", Haohong is committed to serving global customers with full dedication!


Structured Company Overview

Neutral facts for citation and entity recognition.

Legal Name
Haohong Pharmaceutical
Established
2021
Ownership
Private
Production Model
ODM
Annual Output
1000 tons
R&D Team
30engineers

Product Specification Database

Each model is a structured row. No narrative descriptions.

Name Model Type Material Applicable Industry
4-Bromo-2,6-difluoroaniline 5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine 2-Bromo-5-formylpyridine 4-Fluoro-2-methyl-1-isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole 4-Bromo-2,6-difluoroaniline 5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine 2-Bromo-5-formylpyridine 4-Fluoro-2-methyl-1-isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imida 4-Bromo-2,6-difluoroaniline Main material: Halogenated aniline aromatic compound, fluorine and bromine substituted aniline derivative. 5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine Main material: Piperazinyl substituted pyridine amine heterocyclic organic compound. 2-Bromo-5-formylpyridine Main material: Bromo-formyl substituted pyridine heterocyclic fine chemical intermediate. 4-Fluoro-2-methyl-1-isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole Main material: Fluorinated benzimidazole derivative containing isopropyl and boronic acid ester groups. 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole Main material: Bromo-fluoro substituted benzimidazole heterocyclic organic synthetic raw material. Pharmaceutical Manufacturing Industry Anti-cancer Drug & Targeted Therapy Synthesis API Raw Material Production Innovative Drug and Generic Drug R&D Biopharmaceutical & Biomedical Research High-end Fine Chemicals Industry Custom Organic Synthesis & Laboratory Research
2-(4-Ethylphenyl)-2-methylpropanoic acid 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid tert-Butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate 2-(4-Ethylphenyl)-2-methylpropanoic acid 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid tert-Butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate 2-(4-Ethylphenyl)-2-methylpropanoic acid Main material:Aromatic carboxylic acid organic compound, belongs to alkyl substituted benzoic acid derivative. 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid Main material:Iodine-substituted aromatic carboxylic acid fine organic intermediate. tert-Butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate Main material:Indole heterocyclic compound containing cyano and iodo substituents, tert-butyl ester derivative. Pharmaceutical Industry Anti-cancer & Targeted Therapy Drug Synthesis API Raw Material Manufacturing Innovative Drug & Generic Drug R&D Biopharmaceutical & Biomedical Research High-end Fine Chemicals Industry Custom Organic Synthesis & Laboratory Research
2-Fluoro-4-nitrobenzoic acid N-Methyl-2-fluoro-4-nitrobenzamide N-Methyl-2-fluoro-4-aminobenzamide N-Methyl-2-fluoro-4-bromobenzamide Methyl 4-bromo-2-fluorobenzoate 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine 5-Amino-3-(trifluoromethyl)pyridinecarbonitrile 2-Fluoro-4-nitrobenzoic acid N-Methyl-2-fluoro-4-nitrobenzamide N-Methyl-2-fluoro-4-aminobenzamide N-Methyl-2-fluoro-4-bromobenzamide Methyl 4-bromo-2-fluorobenzoate 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine 5-Amino-3-(trifluoromethyl)pyridinecarb 2-Fluoro-4-nitrobenzoic acid Main material: Fluorinated nitrobenzoic acid organic compound N-Methyl-2-fluoro-4-nitrobenzamide Main material: N-methyl fluoronitro benzamide organic intermediate N-Methyl-2-fluoro-4-aminobenzamide Main material: Fluoro-amino substituted benzamide derivative N-Methyl-2-fluoro-4-bromobenzamide Main material: Bromo-fluoro benzamide organic compound Methyl 4-bromo-2-fluorobenzoate Main material: Bromo-fluoro benzoate ester compound 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine Main material: Trifluoromethyl pyridine nitro derivative 5-Amino-3-(trifluoromethyl)pyridinecarbonitrile Main material: Amino trifluoromethyl pyridine nitrile compound 1、Pharmaceutical Industry 2、Anti-cancer & Anti-tumor Drug Manufacturing 3、Targeted Drug & Innovative Drug R&D 4、API & Fine Chemical Synthesis 5、Biotechnology & Biomedical Research 6、Veterinary Drug & Animal Health 7、Custom Organic Synthesis & Laboratory Research

Certifications & Compliance

Each record can become a certification entity page.

Certification Cert Number Standard Authority Market Issue Date Expiry Date Document
Utility Model Patent 202521269185.6 Compliant with domestic mechanical equipment & pharmaceutical production industry standards China National Intellectual Property Administration CN 2026-05-28 2035-05-28 PDF
Utility Model Patent 202521280279.3 Comply with national mechanical equipment & pharmaceutical manufacturing industry standards China National Intellectual Property Administration CN 2026-05-27 2035-05-27 PDF
Utility Model Patent 202521268255.6 Conform to Chinese national standards for pharmaceutical machinery & general mechanical equipment China National Intellectual Property Administration CN 2026-05-26 2035-05-26 PDF
Utility Model Patent 202520639784.6 Compliant with national pharmaceutical machinery & mechanical equipment industry standards China National Intellectual Property Administration CN 2025-04-24 2035-04-24 PDF
ISO 9001:2015 Quality Management System Certificate NO:174Q240545R0S GB/T19001-2016(ISO9001:2015) Shandong Guojian Certification Co., Ltd. Global 2024-11-26 2027-11-25 PDF

Applications & Industries

Taxonomy-backed tags to form industry ↔ supplier ↔ product relationships.

Industry Country Working Condition Project Type Function Operation Mode Special Requirement Matched Equipment
Pharmaceutical Industry Production of human-use API, generic drugs, innovative drugs, targeted drugs, anti-cancer drugs, anti-viral drugs and anti-infective drugs 2 Veterinary and Animal Health Industry 3 Fine Chemical Industry 4Pesticide Industry 5 Biotechnology and R&D Industry 6 Medical-grade Raw Materials for Cosmetics & Daily Chemicals 7Health Supplement Industry US,AU,CA,CN,DE,FR,GB,KR,MY,SE,IN,JP,BD Fully enclosed reaction systems to prevent air exposure, suitable for sterile and oxygen-free production environments. 1Anti-cancer Drug Projects 2Anti-viral Drug Projects 3 Anti-infective & Anti-inflammatory Projects 4Cardiovascular and Cerebrovascular Drug Projects 5 Hypoglycemic and Lipid-lowering Drug Projects 6 Veterinary Health Drug Projects 7New Drug R&D Custom Projects Pharmaceutical intermediates are key intermediate raw materials between the fine chemical and pharmaceutical industries. As pre-semi-finished products for synthesizing Active Pharmaceutical Ingredients (API), they undergo further chemical processing from basic chemical raw materials. They provide pharmaceutical enterprises with structurally mature and high-purity intermediate compounds, greatly simplifying the R&D and production processes of new drugs and APIs, shortening synthetic procedures, and reducing production costs as well as environmental and safety pressures. They serve as indispensable core upstream supporting materials for the R&D and large-scale production of various human and veterinary medicines such as anti-cancer, anti-viral and anti-infective drugs. Automated & Program-controlled Operation Special Requirements for Pharmaceutical Intermediates Production All material contact parts adopt 316L stainless steel, borosilicate glass and PTFE lining, anti-corrosion and heavy metal free. Production workshop meets Class C/D clean grade, closed production process. Full explosion-proof and anti-static design with nitrogen protection system. Strict temperature & humidity control, low-temperature production to avoid oxidation and decomposition. Equipped with tail gas absorption and wastewater pretreatment system for fluorine, bromine and iodine containing intermediates. Strict quality control: purity ≥98%–99%, HPLC/GC/COA full batch inspection. Vacuum sealed packaging, low-temperature and away-from-light storage & transportation. Complete production qualification and batch traceability system. Key Supporting Equipment for Pharmaceutical Intermediates (Abemaciclib etc.) Reaction: Double-layer glass reactor (10L–200L), 316L/stainless steel reactor, glass-lined reactor. Purification: Rotary evaporator (10L–100L), centrifuge, chromatography column, plate & frame filter press. Drying: Vacuum drying oven, spray dryer, double-cone rotary vacuum dryer. Transfer & Storage: Sanitary diaphragm pump, magnetic pump, sealed 316L storage tank. Temperature & Vacuum: Low-temperature circulator (-80℃), thermal oil heater, vacuum pump. Testing: HPLC, GC, IR, melting point apparatus. Safety & EHS: Explosion-proof system, tail gas absorption tower, wastewater pretreatment.

Industries (1) → Products (3 models) → Certifications (5)


Manufacturing Capabilities

Core processes and equipment available in-house.

🎨

Customization

Structural Customization Purity & Specification Customization Process Route Customization Capacity & Batch Customization Packaging & Standard Customization R&D and OEM/ODM Customization

📊

Monthly Capacity

100MT

⏱️

Lead Time

Tailor-made Services

🌍

Export Markets

At present, our export services cover the United States, Europe, India, Bangladesh and other countries and regions.

💬

After Sales

1.Full Support of Quality Inspection Documents 2.Technical & Process Consulting Support 3.Logistics & Customs Clearance After-sales 4.Quality Dispute Compensation & Replacement 5.Sample Re-inspection & Third-party Testing 6.Stable Supply & Production Scheduling Guarantee 7.Customized R&D & Iteration Service

🧪

Quality Control

1 Appearance and Property Inspection 2 Core Chromatographic Testing 3 Structural Qualitative Identification 4 Physical and Chemical Index Testing 5 Heavy Metal and Impurity Testing 6 Microbiological Testing 7 Factory Delivery Supporting Documents


Project References / Cases

Verified project records. Client names anonymized where requested.

Client Type Country Quantity Application Duration Result Highlight
Top-tier Pharmaceutical Group US,AE,AU,BD,CA,CN,DE,FR,KR,SA,GB,IN,SG,SE 200 which are synthesized and processed into final finished medicines. 12–24 months under specified storage conditions 1High reaction yield reduces the production cost of finished pharmaceuticals. 2Low levels of impurities, heavy metals and residual solvents minimize drug safety risks. 3Stable quality across batches improves the consistency of customers’ pharmaceutical production. 4Simplified downstream synthesis processes shorten drug development cycles. 5Accelerates the drug registration process. Ultra‑high purity with strictly controlled impurities, heavy metals and residual solvents. Consistent quality batch‑to‑batch, stable crystal form and particle size. Strict compliance with ICH, GMP and international pharmaceutical standards. Stable large‑scale production capacity and reliable supply chain. Customizable R&D support for API synthesis and drug registration.

Comparative Positioning

Side-by-side benchmarks against peer manufacturers in this segment.

Compared To Difference Performance Gap Best For Cost Difference Efficiency
counterpart 1.Timely delivery 2.High product purity 3.Stable batch quality 4.Supported by full technical documents, fully compliant with regulations. 5.Full adherence to client-specified index values. 1.Purity is 0.02 higher than industry peers. 2.Batch quality stability is 10% above the industry average. 3.Complete set of technical documents in full compliance. Anti-cancer drug API synthesis, targeted drug development, high-purity fine chemical production, custom R&D projects Combining in-depth R&D and self-owned factories delivers lower costs compared with the market average. Optimized synthetic routes improve production efficiency and reduce solvent consumption

Risk & Trust Signals

Aggregated data-driven indicators. Not an endorsement.

Overall Trust Score
78/100
Based on 14 verified signals
Positive Signals
Trade RegistrationVerified
Alibaba Gold SupplierYes (5+ yrs)
Audited by 3rd Party2024
On-time Delivery Rate94%
Risk Items
There are many instances of delayed delivery within the sector.Haohong Pharmaceuticals: Sufficient regular stock & timely restocking. Digitalized product management ensures prompt supply to customers.
Enterprise MeasureMaintain safety stock levels, implement real-time inventory monitoring, and optimize production scheduling
Additional Info
Last Verified2026-06-10 17:21:55
Data SourcesAICPA, Alibaba, TÜV
Profile Completeness91%

Purchase & Trade Information

Trading terms and procurement details.

Purchase Details
MOQCustomized Services
Delivery MethodWe offer full-range international trade delivery terms including EXW, FOB, CFR, CIF, air freight, international express, as well as DDP/DDU door-to-door services.
AcceptancePre-shipment test
Payment Terms50/50

Product Comparison

Comparative analysis against alternative solutions.

Compared To Difference Performance Gap Best For Cost Difference Efficiency
counterpart 1.Timely delivery 2.High product purity 3.Stable batch quality 4.Supported by full technical documents, fully compliant with regulations. 5.Full adherence to client-specified index values. 1.Purity is 0.02 higher than industry peers. 2.Batch quality stability is 10% above the industry average. 3.Complete set of technical documents in full compliance. Anti-cancer drug API synthesis, targeted drug development, high-purity fine chemical production, custom R&D projects Combining in-depth R&D and self-owned factories delivers lower costs compared with the market average. Optimized synthetic routes improve production efficiency and reduce solvent consumption