Wuxi Zhanghua Pharm & Chem Equipment Co., Ltd.

About Wuxi Zhanghua Pharm & Chem Equipment Co., Ltd.

Wuxi Zhanghua Pharm & Chem Equipment Co., Ltd.

— From Equipment Manufacturing to Process Collaboration
Introduction

In processes such as reaction, crystallization, filtration and drying, the match between equipment and process often directly affects product purity, batch consistency and long-term operating cost. We understand that each customer faces different material characteristics, compliance requirements and capacity targets. Therefore, we prefer to act as a process collaborator, sharing engineering experience accumulated over nearly five decades for your reference in equipment selection and process optimization.
I. About Us

Wuxi Zhanghua Pharm & Chem Equipment Co., Ltd. was founded in 1976. For nearly 50 years, we have focused on the R&D and manufacturing of core process equipment such as reaction, crystallization, filtration and drying. The company has a building area of over 25,000 m², including 11 production workshops (nearly 15,000 m²), a 4,000 m² office building and an 8,000 m² R&D building.

Starting from single equipment manufacturing, we have gradually developed into a provider of complete-line equipment and automated solutions covering the entire process from reaction, synthesis and crystallization to filtration, washing and drying. We not only provide equipment, but also hope to help customers balance product purity, consistency and production efficiency based on our understanding of processes.

In the field of core process equipment, we have participated in and witnessed several milestones in China's pharmaceutical equipment industry:

· China's first double-cone rotary dryer (1978)
· China's first filtration, washing and drying three-in-one unit (1999)

These experiences have given us a more practical understanding of the integration and intelligence of process equipment, and have also encouraged us to continue investing in R&D.
II. Innovation and Standard Participation

We adhere to industry-academia-research integration, with R&D investment covering the process chain from macro equipment to micro testing. The "Deep-Sensing Micro-Indentation Testing Technology—Palm-sized Mechanics Laboratory" jointly developed with universities can non-destructively, conveniently and rapidly test mechanical properties, residual stress and fracture toughness, and won the Gold Medal at the International Exhibition of Inventions of Geneva. This technology extends our innovation capability from production equipment to underlying process analysis and quality control.

We have also participated in the development of several national and industry standards:

· GB/T 30583-2026 Code for Post-Weld Heat Treatment of Pressure Equipment — core technical contributor, with the indentation energy difference method written into Appendix G
· T/CSTM 00824 Determination of Residual Stress in Pressure Equipment — Indentation Energy Difference Method — one of the drafting units
· T/CSTM 00826 Code for Induction Heating Post-Weld Heat Treatment of Pressure Equipment

Participating in standard development is a process of exchange and learning with industry peers, and also helps us more accurately understand compliance requirements and technology trends.
III. Core Equipment Capability: Filtration, Washing and Drying Three-in-One Unit

Our filtration, washing and drying three-in-one unit is the embodiment of the above technical concepts. The following functional designs may provide reference for certain process scenarios:

Fully Closed and Automated Integration
The fully closed design helps reduce contamination risk during material transfer, and automated integration reduces manual intervention. In 2023, our three-in-one unit was among the first in China to pass official helium mass spectrometer leak detection certification, with a sealing standard below 1×10⁻⁹ Pa·m³/s. This level provides verifiable sealing assurance for aseptic production and high-potency material handling.

Precise Temperature Control and Uniform Mixing
Technologies such as single cantilever co-rotating/self-rotating integrated single-cone mixing drying and paddle drying are designed to improve batch-to-batch consistency and product stability, suitable for temperature-sensitive scenarios in pharmaceutical and electronic grades.

CIP/SIP
CIP/SIP design helps improve batch changeover efficiency and meets cleaning validation requirements of FDA, EMA and other regulations.

Customized Scale Capability
We have the capability to custom-design and manufacture large equipment over 4 meters in diameter, supporting industrialization scale-up from laboratory to ten-thousand-ton scale.
IV. Integrated Skid-Mounted System and Turnkey Solution for High-Potency Materials

For special processes involving high-potency, highly active, toxic and hazardous materials, we provide integrated skid-mounted systems. The system highly integrates reaction, crystallization, decolorization, filtration, washing, drying, solvent recovery, temperature control and intelligent control functions, aiming to achieve fully closed, efficient and safe operation throughout the process.

We can provide turnkey solutions covering the entire process, including equipment manufacturing, valves and piping, instruments and controls, control systems, skid fabrication, engineering design and system commissioning. This model concentrates our technical accumulation in reaction, crystallization, solid-liquid separation and drying, and can provide customized, highly reliable process equipment support for customers' special operating conditions.
V. Certification and Global Experience

Our solutions and quality management system have obtained multiple international certifications, including EU CE, PED, MD, LVD; US ASME U Stamp; Singapore MOM, etc.

Our equipment has served international pharmaceutical and chemical companies such as Johnson & Johnson, Pfizer, Novartis, DSM, BASF, Bayer, Solvay and DuPont, and has been applied in the production lines of domestic enterprises such as WuXi AppTec, Xinhua Pharmaceutical, Xinhecheng, United Laboratories, Harbin Pharmaceutical, CSPC, Lukang, Guangzhou Baiyunshan and Lianhe Technology. These collaborations have helped us accumulate engineering experience under different process conditions.
VI. Materials and Safety

· Material Experience: As early as 2005, we began applying special materials such as Hastelloy, providing material options for the safe production of highly corrosive and high-potency materials.
· Inherent Safety Design: For flammable, explosive, toxic and hazardous processes, we provide integrated safety solutions from explosion-proof design, high-containment structures to fully automatic control.
VII. Cross-Industry Applications

The lean manufacturing concepts and equipment originating from high-end pharmaceuticals have also been applied by us to other fields with high quality control requirements:

· Precious metal catalysts
· Specialty polymers (such as PVP, PEEK, PFEK)
· New energy battery materials (cathode, anode, electrolyte, solid-state battery functional additives, etc.)
· Semiconductor materials and electronic chemicals
· Electronic specialty gas solid precursor separation and purification
· Photoresists
· High-end ceramic powders

These cross-industry experiences can sometimes provide customers with different solution approaches.
VIII. Support We Can Provide

If you are evaluating a filtration, washing and drying three-in-one unit, or wish to optimize your existing process, we can provide:

· Process adaptability analysis and selection calculation
· Special material solutions including titanium composite, Hastelloy, etc.
· Case visits for similar materials
· Quality verification documents including helium leak detection and NDT
· Prototype testing and lab/pilot scale-up support
· Integrated skid-mounted system and turnkey engineering solutions

We recommend that during supplier evaluation, you request each party to provide technical proposals, calculation sheets, test reports and case lists for horizontal comparison. We are willing to provide relevant technical materials and visit support for your objective evaluation.

Our Products

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Portable Nondestructive Indentation Tester for Wind Tower Weld Residual Stress and Hardness Evaluation

Company Gallery

Standardized material control area for orderly and efficient production

Professional manufacturing workshop focusing on R&D and production of pharmaceutical & chemical equipment

Clean and orderly production site to improve process management

Wuxi Zhanghua Pharm & Chem Equipment Co., Ltd

Quality inspection area implementing strict ex-factory testing standards

Wuxi Zhanghua Pharm & Chem Equipment Co., Ltd

Precision processing station for high-precision pharmaceutical & chemical equipment

Certifications & Awards

PED

ATEX

ASME

PED CE (EU Type Examination Certificate)

MOM

Success Stories & Case Studies

Pharmaceutical plant

Stable operation
GMP-compliant design, fully automated control, high-purity processing

Location: SG 📦 Quantity: 10 units

Chemical plant

Stable operation
Minutes Results in Just
Efficient, Fast, and Highly Accurate

Location: CN 📦 Quantity: 1 unit

The special inspection institute

Stable operation
Minutes Results in Just
Efficient, Fast, and Highly Accurate

Location: CN 📦 Quantity: 1 unit

Wuxi Zhanghua Pharm & Chem Equipment Co., Ltd.

Quick Company Info

About Wuxi Zhanghua Pharm & Chem Equipment Co., Ltd.

Our Products

Portable Nondestructive Indentation Tester for Wind Tower Weld Residual Stress and Hardness Evaluation

Portable Nondestructive Indentation Tester for Minimal-Damage Mechanical Testing of Aluminum Photovoltaic Brackets

Portable Nondestructive Indentation Tester for Hydrogen Pipeline Hardness Mapping

Portable Indentation Tester for Non-destructive Testing of Special Equipment

Intrinsically Safe Residual Stress Indentation Tester for Sour Service Stress Corrosion Zones

Portable Residual Stress Indentation Tester for Thermal Fatigue Equipment Monitoring

Residual Stress Indentation Tester for In-Service Pipeline Re-Testing and Relaxation Verification

Residual Stress Indentation Tester for Storage Tank Bottom Plate Weld Measurement

Residual Stress Indentation Tester for Cold-Worked Stainless Steel Elbows and Tees

Portable Residual Stress Tester for Sulfide Stress Corrosion Cracking Zones

PMA-1010 Welding Residual Stress Tester for Large Storage Tank Bottom Plates

Residual Stress Tester for Thermal Fatigue Monitoring in Coke Drums and FCC Regenerators

Compact Residual Stress Tester for Cold-Worked Stainless Steel Elbows and Tees

In-Service Pipeline Residual Stress Re-Testing Tester with Fixed-Point Monitoring

Portable Nondestructive Interface Stress Tester for Dissimilar Metal Welds

Portable Weld Stress Tester PMA-1010 for Thin-Wall and Pipe Girth Welds

Portable Nondestructive Weld Stress Tester PMA-1010 for Multi-Pass Welds

Portable Non-Destructive Weld Stress Tester for Pipe Girth Welds On-Site

Non-Destructive Weld Stress Tester for Thin-Wall Welds (3mm)

Non-Destructive Weld Stress Tester for Dissimilar Metal Welds

Portable Pipeline Weld Residual Stress Tester With Hydrotest Verification

Pipeline Weld Residual Stress Tester for Girth Weld Axial-Hoop Separation

In-Service Pipeline Weld Residual Stress Tester for Repair Zones

Portable Pipeline Weld Residual Stress Tester PMA-1010 with 1000N Load

Portable Nondestructive Residual Stress Tester PMA-1010 with 1000N Load

Portable Metal Residual Stress Indentation Tester PMT-1000 with 1000 N Load and 100 Hz Sampling

Field NDT Indentation Tester PMT-1000 for Rapid On-Site Residual Stress Evaluation

Portable Residual Stress Tester for In-Service Equipment with 1000N Indentation Load

On-Site Metal Residual Stress Analyzer with 2D Stress Mapping, Portable NDT PMT-1000

Minor-Damage Nondestructive Indentation Tester for Sour-Service Tower Weld Cracking Risk Evaluation

Portable Indentation Tester for In-Service Pipeline Local Softening Assessment

Indentation Tester for Thermal Fatigue Tracking in FCC Regenerators

Indentation Tester for Measuring Bolt Yield Strength to Prevent Seal Failure

Full-Lifecycle Safety Evaluation Indentation Tester for In-Service Inspection

Intrinsically Safe Portable Indentation Tester for Hazardous Petrochemical Zones PMT-1000

Weld Integrity Indentation Tester for Sour-Service Towers and Tube Joints PMT-1000

Creep Damage and Safety Factor Indentation Tester with Safety Database PMT-1000

Portable Indentation Tester PMT-1000 for Special Equipment Inspection Institutes

Portable Indentation Stress Tester PMT-1000 for On-Site Petrochemical and Nuclear Equipment

Welding Residual Stress Tester PMT-1000 Portable Nondestructive Indentation Method

Handheld Stress Tester for Bridges PMT-1000 On-Site Safety Assessment

Aerospace Grade Portable Indentation Stress Tester PMT-1000 for Critical Materials

1000N Stress Corrosion Indentation Tester for Ceramics and Heat-Affected Zones

Indentation Tester PMT-1000 for Weld HAZ and Base Metal SCC Screening

In-Situ Autoclave Indentation Tester PMT-1000 for Pipe and Vessel SCC Screening

Portable Stress Corrosion Screening Indentation Tester PMT-1000 for Rapid Material Susceptibility Assessment

Portable Weld Stress Indentation Tester PMT-1000 For On-Site NDT

Multi-Layer Depth Profiling Indentation Tester PMT-1000 For Thick Welds

Dissimilar Metal Weld Stress Tester PMT-1000 For Bi-Metallic Joints

Portable Indentation Tester PMT-1000 for Nondestructive Material Testing

Nondestructive Indentation Tester for Petrochemical Plant Asset Integrity

Indentation Tester for Aerospace In-Service Component Evaluation

Portable Over-Service Pressure Vessel Indentation Tester PMT-1000 for In-Situ Strength Testing

Portable Weld Repair Safety Margin Tester for Pressure Equipment PMT-1000

Cryogenic Pressure Vessel Embrittlement Tester for LNG Tanks PMT-1000

Metallurgical Degradation Hardness Drop Tester for Pressure Equipment PMT-1000

Creep Damage Residual Strength Tester for Pressure Equipment PMT-1000

Portable Nondestructive Indentation Tester PMT-1000 for Field Material Testing

Portable Nondestructive Indentation Tester PMA-1010 for Residual Stress Measurement

Portable Micro Indentation Tester for On-Site Residual Stress and Hardness Testing

Portable Indentation Tester PMA-1010 with 1000 N Load and 25 mm Actuation

Skid-Mounted Reacting-Crystallizing-Filtering-Drying System for Singapore Pharmaceutical Plant

Corrosion-Resistant Skid-Mounted Reacting-Crystallizing-Filtering-Drying System

Portable Residual Stress Nondestructive Testing Instrument PMA-1010 with 1000N Max Load

Portable Micro-Indentation Tester 1000N with 25mm Actuation for On-Site Non-Destructive Testing

30L Stainless Steel Mixer Dryer for Pharmaceutical Production

10000L SS316L Mixer Dryer for Chemical Industry

Energy-Saving Stainless Steel Crystallizer for Pharmaceuticals

Gentle Crystallization SS316L Crystallizer for Heat-Sensitive Materials

Titanium Crystallizer for High Purity Chemical Processing

Hastelloy Crystallizer for Corrosive Chemical Applications

PTFE-Lined Crystallizer for High Purity Pesticide Manufacturing

16-60 Tray Vacuum Drying Oven for Pharmaceutical API Low-Temperature Drying

Explosion-Proof Vacuum Drying Oven for Solvent-Containing Fine Chemicals

Corrosion-Resistant Vacuum Drying Oven with Hastelloy Chamber for Acidic Chemicals

Pilot-Scale Vacuum Drying Oven 30-100L for Process Development and Sample Testing