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2-Bromo-5-formylpyridine CAS 100422-52-6 for Abemaciclib Synthesis

Quantity:
SKU: 8820573202
Model: 4-Bromo-2,6-difluoroaniline 5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine 2-Bromo-5-formylpyridine 4-Fluoro-2-methyl-1-isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

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Product Details

2-Bromo-5-formylpyridine CAS 100422-52-6 for Abemaciclib Synthesis

Heterocyclic Intermediate for Anticancer Drug Manufacturing

Product Summary

2-Bromo-5-formylpyridine (CAS 100422-52-6) is a high-purity heterocyclic intermediate used in the synthesis of Abemaciclib. Its bromo and formyl functionalities enable key cross-coupling reactions, making it essential for efficient API production.

Key Selling Points

  • Reactive Functional Groups: Bromo and formyl groups facilitate diverse chemical transformations for Abemaciclib synthesis.
  • Purity ≥98.0% (GC/HPLC): Ensures minimal impurities and consistent reaction outcomes.
  • Stable Storage: Sealed, dry, refrigerated preservation maintains product integrity.
  • Defined Thermal Properties: Melting point 78–82°C and boiling point 286.3°C offer predictable behavior.
  • Heterocyclic Intermediate: Directly used in the commercial production of Abemaciclib API.

Technical Specifications

ParameterValue
CAS Number100422-52-6
Molecular FormulaC₆H₄BrNO
Molecular Weight185.91
AppearanceWhite to light yellow solid
Purity≥98.0% (GC/HPLC)
Melting Point78–82 °C
Boiling Point286.3±30.0 °C
Storage ConditionsSealed, dry, refrigerated preservation

Models and Options

Available in research and commercial quantities. Custom packaging and documentation.

Materials and Structure

Bromo-formyl substituted pyridine heterocyclic fine chemical intermediate. The combination of bromine and aldehyde groups provides versatile reactivity for building the Abemaciclib backbone.

Applications

Pharmaceutical manufacturing, anti-cancer drug synthesis, and heterocyclic chemistry. Key intermediate for Abemaciclib production.

FAQ

What purity is supplied?

We supply ≥98.0% purity as per GC/HPLC analysis.

How should it be stored?

Sealed, dry, and refrigerated to maintain stability.

Is it suitable for scale-up?

Yes, we support commercial production quantities.

Do you provide impurity profiles?

Yes, detailed COA includes impurity data.

Can you provide samples?

Custom evaluations can be arranged.

Inquiry Information

Contact Xu Tianxia: Xutx@haohong-pharma.com, +86 180-6854-1569.