4-Bromo-2,6-difluoroaniline
CAS: 1868-81-7
Molecular Formula: C₆H₄BrF₂N
Molecular Weight: 207.91
Appearance: White to off-white crystalline solid
Purity: ≥98.0% (HPLC/GC)
Density: 1.768±0.06 g/cm³
Boiling Point: 239.4±35.0 °C
Melting Point: 57–61 °C
Storage: Sealed, dry, keep away from light at 2–8 °C
Application: Abemaciclib pharmaceutical intermediate
5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine
CAS: 398565-53-2
Molecular Formula: C₁₂H₂₀N₄
Molecular Weight: 220.03
Appearance: Off-white to light yellow solid
Purity: ≥98.0% (HPLC)
Boiling Point: 368.5±42.0 °C
Density: 1.124±0.06 g/cm³
Storage: Sealed, low temperature and light protection
Application: Key intermediate for Abemaciclib
2-Bromo-5-formylpyridine
CAS: 100422-52-6
Molecular Formula: C₆H₄BrNO
Molecular Weight: 185.91
Appearance: White to light yellow solid
Purity: ≥98.0% (GC/HPLC)
Melting Point: 78–82 °C
Boiling Point: 286.3±30.0 °C
Storage: Sealed, dry, refrigerated preservation
Application: Heterocyclic intermediate for Abemaciclib synthesis
4-Fluoro-2-methyl-1-isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole
CAS: 1356339-86-7
Appearance: White to off-white solid
Purity: ≥98.0% (HPLC)
Storage: Sealed, inert gas protection, 2–8 °C, avoid light
Application: Boronic acid ester intermediate for Abemaciclib
6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole
CAS: 1356339-85-6
Appearance: White to light beige solid
Purity: ≥98.0% (HPLC)
Storage: Sealed, dry, low temperature and light-proof storage
Application: Core benzimidazole intermediate for Abemaciclib R&D and production
