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High Purity 2-Fluoro-4-Nitrobenzoic Acid for Apalutamide Synthesis

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SKU: 1959464418
Model: 2-Fluoro-4-nitrobenzoic acid N-Methyl-2-fluoro-4-nitrobenzamide N-Methyl-2-fluoro-4-aminobenzamideN-Methyl-2-fluoro-4-bromobenzamideMethyl 4-bromo-2-fluorobenzoate 5-Amino-3-(trifluoromethyl)pyridinecarbonitrile

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Haohong Pharmaceutical
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Product Details

2-Fluoro-4-Nitrobenzoic Acid for Apalutamide Intermediate

2-Fluoro-4-nitrobenzoic acid is a key starting material for Apalutamide intermediates. This high-purity compound (≥98.0%) is available in white to light yellow solid form with a melting point of 170–176 °C. It serves as a foundational building block in pharmaceutical synthesis, particularly in the production of anti-cancer drugs.

Key Selling Points

  • High purity (≥98.0%): Ensures consistent quality and reduces downstream purification effort, improving overall yield.
  • Stable supply: Produced by Haohong with annual output of 1000 tons, ensuring reliable availability for large-scale production.
  • ICH/GMP compliance: Our production adheres to international pharmaceutical standards, ensuring safety and regulatory readiness.
  • Custom synthesis support: We offer custom synthesis from gram to hundreds of kilograms, supporting your R&D and production needs.

Technical Specifications

Item Specification
CAS Number 403-24-7
Molecular Formula C₇H₄FNO₄
Molecular Weight 185.11
Appearance White to light yellow solid
Melting Point 170–176 °C
Boiling Point 352.5±27 °C (predicted)
Density 1.568±0.06 g/cm³ (predicted)
Purity ≥98.0%
Storage Sealed, dry, room temperature

Models and Options

This product is available as a standalone intermediate. We offer custom packing options (e.g., 25kg drums) and can provide documentation such as COA and HPLC analysis upon request.

Materials and Structure

Main material: Fluorinated nitrobenzoic acid organic compound. The molecular structure contains a fluorine atom and a nitro group on a benzoic acid backbone, which is essential for further functionalization in Apalutamide synthesis.

Applications

  • Pharmaceutical industry: As a key intermediate for anti-cancer drug synthesis.
  • Targeted drug & innovative drug R&D.
  • API & fine chemical synthesis.

Case Study

A top-tier pharmaceutical group has used our intermediates for the production of finished medicines. The ultra-high purity and strictly controlled impurities helped reduce safety risks and improved production consistency, as reported in our case study.

FAQ

What is the purity of this product? ≥98.0% as per our specification.
What is the packaging available? We offer custom packaging, typically 25kg drums, but we can adjust based on your needs.
Can you provide samples for testing? Yes, we offer samples for evaluation. Please contact us for details.
What is your delivery time? We provide various delivery terms including EXW, FOB, CIF, and DDP. Lead time depends on order quantity.
Do you have certifications? We hold ISO 9001:2015 and multiple utility model patents for production equipment.
Can you support custom synthesis? Yes, we provide custom synthesis from gram to hundreds of kilograms.

Inquiry Information

For price and availability, contact: Xu Tianxia, Email: Xutx@haohong-pharma.com, Tel: +86 180-6854-1569.

2-Fluoro-4-nitrobenzoic acid Apalutamide intermediate white solid