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Methyl 4-Bromo-2-Fluorobenzoate for Apalutamide Synthesis

Quantity:
SKU: 3514302898
Model: 2-Fluoro-4-nitrobenzoic acid N-Methyl-2-fluoro-4-nitrobenzamide N-Methyl-2-fluoro-4-aminobenzamide N-Methyl-2-fluoro-4-bromobenzamide Methyl 4-bromo-2-fluorobenzoate 5-Amino-3-(trifluoromethyl)pyridinecarbonitrile

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Haohong Pharmaceutical
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Product Details

Methyl 4-Bromo-2-Fluorobenzoate: Apalutamide Intermediate

Methyl 4-bromo-2-fluorobenzoate is an ester intermediate used in the synthesis of Apalutamide. This compound appears as a white to off-white solid with a purity of ≥98.0% (GC). Its ester functional group is valuable for further transformations in the synthetic pathway.

Key Selling Points

  • High purity (≥98% GC): Ensures high yields in subsequent reactions.
  • Versatile ester functionality: Provides multiple synthetic pathways for Apalutamide production.
  • Consistent quality: Batch-to-batch consistency ensures reproducibility.
  • Scalable supply: Annual production capacity of 1000 tons supports large-scale orders.

Technical Specifications

ItemSpecification
CAS Number179232-29-2
Molecular FormulaC₈H₆BrFO₂
Molecular Weight233.03
AppearanceWhite to off-white solid
Melting Point58–62 °C
Boiling Point272.7±25 °C
Density1.577±0.06 g/cm³
Purity≥98.0% (GC)
StorageSealed, dry, room temperature

Models and Options

Available in various quantities; custom packaging available. We can provide GC analysis and COA.

Materials and Structure

Main material: Bromo-fluoro benzoate ester compound. The ester group is a protecting group that can be hydrolyzed to the acid or converted to amides for Apalutamide construction.

Applications

  • Pharmaceutical intermediate for anti-cancer drugs.
  • Organic synthesis for APIs.
  • Fine chemical production.

Case Study

Our case study indicates that this intermediate helps reduce production costs and accelerate drug registration processes.

FAQ

What is the purity of this compound?≥98.0% (GC).
Can you provide a sample for testing?Yes, we can provide samples for evaluation.
Do you have any documentation?We provide COA, HPLC/GC chromatograms, and MSDS upon request.
What is the delivery time?Delivery time varies with order size; we can discuss during inquiry.
What are the payment terms?We offer 50/50 payment terms.
Can you customize packaging?Yes, we can customize packaging according to your requirements.

Inquiry Information

Contact: Xu Tianxia, Email: Xutx@haohong-pharma.com, Tel: +86 180-6854-1569.

Methyl 4-bromo-2-fluorobenzoate white solid